Table 3 Distribution of mutations in the tumour-derived VH sequences

From: Effect of Helicobacter pylori eradication on ongoing mutation of immunoglobulin genes in gastric MALT lymphoma

  

Expected

Observed

 

Case

Region

R

S

R

S

P a

1a

CDR

2

1

5

0

 
      

0.04

 

FR

5

2

2

3

 

1b

CDR

4

1

7

1

 
      

0.02

 

FR

8

3

5

3

 

2

CDR

0

0

2

0

 
      

0.10

 

FR

2

1

1

0

 

3

CDR

2

0

3

0

 
      

0.09

 

FR

3

1

2

1

 

4

CDR

2

0

2

0

 
      

0.27

 

FR

3

1

3

1

 

5

CDR

2

0

2

0

 
      

0.30

 

FR

4

2

4

2

 
  1. aP is the probability of obtaining the number of R mutations found in the CDR by chance.
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