Table 1 Referral guidelines
Cancer | Family history criteria (on the same side of the family) |
|---|---|
Breast cancer | • One first-degree relative diagnosed at 40 years or less. |
• Two first-degree relatives diagnosed at 60 years or less. | |
• Three first- or second-degree relatives diagnosed at any age. | |
• One first-degree male breast cancer. | |
• A first-degree relative with bilateral breast cancer. | |
Breast/ovarian cancer | • At least one breast and one ovarian cancer in first-degree relatives (breast cancer diagnosed under 50 years if only one of each cancer). |
• A first-degree relative who has both breast and ovarian cancer. | |
Ovarian cancer | • Two or more ovarian cancers (at least one first-degree relative). |
Colon cancer | • One first-degree relative diagnosed at 40 years or less. |
• Two first-degree relatives diagnosed at 60 years or less. | |
• Three relatives diagnosed at any age (at least one first-degree relative). | |
• Familial adenomatous polyposis in a first- or second-degree relative. | |
• Hereditary nonpolyposis colorectal cancer (revised Amsterdam criteria) in a first- or second-degree relative. |
