Table 5 Counselling and administrative costs

From: A micro costing of NHS cancer genetic services

 

Counselling and administrative costs

 

Event pathway

Labour (minmax)

Capital (minmax)

Overheads (minmax)

Total (minmax)

1. Family history questionnaire not returned

£9 (£9–£10)

£4 (£2–£5)

£2 (£2–£3)

£16 (£14–£17)

2. Inappropriate referral

£69 (£37–£100)

£17 (£8–£26)

£12 (£6–£18)

£98 (£51–£144)

3. Moderate risk – breast cancer

£66 (£27–£105)

£18 (£8–£28)

£13 (£6–£20)

£97 (£40–£153)

4. Moderate risk – colorectal cancer

£69 (£37–£100)

£17 (£8–£26)

£12 (£6–£18)

£98 (£51–£144)

5. Moderate risk – ovarian or breast ovarian cancer

£105 (£51–£158)

£27 (£17–£37)

£20 (£11–£28)

£151 (£79–£223)

High risk – colorectal (HNPCC)

    

 6. Test cancer-affected relative (mutation found) and test presymptomatic patient

£1068 (£593–£1542)

£188 (£111–£265)

£139 (£99–£180)

£1396 (£803–£1988)

 7. Test cancer-affected relative (no mutation found) and do not test presymptomatic patient

£622 (£338–£906)

£119 (£70–£167)

£85 (£58–£113)

£826 (£466–£1186)

 8. Test subsequent presymptomatic members of a family with an established mutation (MLH1/ MSH2 mutation in family)

£777 (£432–£1121)

£125 (£77–£173)

£95 (£71–£120)

£997 (£579–£1415)

 9. Counsel and arrange presymptomatic care for members of a family with no established mutation

£759 (£415–£1103)

£122 (£74–£171)

£93 (£68–£118)

£975 (£557–£1392)

High risk – colorectal (FAP)

    

 10. Test cancer affected relative (mutation found) and test presymptomatic patient

£1068 (£593–£1542)

£188 (£111–£265)

£139 (£99–£180)

£1396 (£803–£1988)

 11. Test cancer-affected relative (no mutation found) and do not test presymptomatic patient

£622 (£338–£906)

£119 (£70–£167)

£85 (£58–£113)

£826 (£466–£1186)

 12. Test subsequent presymptomatic members of a family with an established mutation (using linkage testing)

£777 (£432–£1121)

£125 (£77–£173)

£95 (£71–£120)

£997 (£579–£1415)

 13. Test subsequent presymptomatic members of a family with an established mutation (using sequence analysis)

£777 (£432–£1121)

£125 (£77–£173)

£95 (£71–£120)

£997 (£579–£1415)

 14. Counsel and arrange presymptomatic care for members of a family with no established mutation

£759 (£415–£1103)

£122 (£74–£171)

£93 (£68–£118)

£975 (£557–£1392)

High risk – breast (BRCA1/2)

    

 15. Test cancer-affected relative (mutation found) and test presymptomatic patient

£705 (£264–£1146)

£181 (£106–£256)

£110 (£67–£153)

£996 (£437–£1555)

 16. Test cancer-affected relative (no mutation found) and do not test presymptomatic patient

£430 (£173–£687)

£115 (£68–£162)

£70 (£42–£98)

£614 (£283–£946)

 17. Test subsequent presymptomatic members of a family with an established mutation

£496 (£170–£822)

£119 (£73–£166)

£72 (£45–£99)

£688 (£288–£1087)

 18. Counsel and arrange presymptomatic care for members of a family with no established mutation

£487 (£165–£809)

£117 (£70–£164)

£71 (£44–£98)

£675 (£279–£1070)

High risk – ovarian or breast ovarian (BRCA1/2)

    

 19. Test cancer-affected relative (mutation found) and test presymptomatic patient

£1068 (£593–£1542)

£188 (£111–£265)

£139 (££99–£180)

£1396 (£803–£1988)

 20. Test cancer-affected relative (no mutation found) and do not test presymptomatic patient

£622 (£338–£906)

£119 (£70–£167)

£85 (£58–£113)

£826 (£466–£1186)

 21. Test subsequent presymptomatic members of a family with an established mutation

£777 (£432–£1121)

£125 (£77–£173)

£95 (£71–£120)

£997 (£579–£1415)

 22. Counsel and arrange presymptomatic care for members of a family with no established mutation

£759 (£415–£1103)

£122 (£74–£171)

£93 (£68–£118)

£975 (£557–£1392)

  1. Costs are rounded to the nearest £1 within each column. HNPCC=hereditary nonpolyposis colorectal cancer; FAP or FAPC=familial adenomatous polyposis coli.