British Journal of Cancer

Table 2 Estimates of LPFS, DMFS and CSS 5 years after treatment, determined according to the Kaplan–Meier method^* and the univariate analyses (log-rank test^**) for various clinicopathological characteristics in our cohort of 82 patients with cervical cancer

From: Correlation between the tumoral expression of β3-integrin and outcome in cervical cancer patients who had undergone radiotherapy

	5 yrs – LPFS*		5 yrs – DMFS*		5 yrs – CSS*
Parameter	%	P -value**	%	P -value**	%	P -value**
Age		0.53		0.60		0.80
<Median	60±8		65±9		51±9
>Median	69±8		74±8		62±8
FIGO stage		0.09^a		0.80		0.25
I/II	72±8		72±8		64±8
III/IV	54±9		64±10		46±9
Histology		0.07^a		0.012^a		0.016^a
Adeno/-squamous	48±14		41±15		34±13
Squamous	68±6		75±6		60±7
Differentiation		0.14		0.62		0.22
Grade 2	56±9		64±10		48±9
Grade 3	78±8		74±9		65±9
Nodal status		0.009^a		0.004^a		0.002^a
Negative	76±6		82±7		69±7
Positive	43±10		47±11		32±10
Haemoglobin		0.03^a		0.89		0.09^a
<Median	51±10		66±11		45±10
>Median	73±7		69±8		61±8
Chemotherapy		0.95		0.56		0.88
Yes	65±10		65±10		55±10
No	64±7		73±7		56±8
Brachytherapy		0.009^a		0.98		0.16
Yes	69±6		68±7		58±7
No	45±13		72±13		45±13
Total dose		0.47		0.81		0.43
<Median	61±9		71±9		55±9
>Median	67±8		67±8		57±9
P53 expression		0.20		0.75		0.20
Negative	71±6		69±7		58±8
Positive	51±12		71±10		51±11
β3 expression		0.007		0.09		0.038
Negative	85±7		85±7		78±8
Weak positive	46±10		67±10		44±10
Strong positive	57±12		50±13		39±12
β3 expression		0.002^a		0.036^a		0.011^a
Negative	85±7		85±7		78±8
Positive	51±8		57±9		41±8

LPFS=local progression-free survival; DMFS=distant metastasis-free survival; CSS=cause-specific survival.
^aMarked parameters were included in multivariate analysis.

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