Table 3 Standardised incidence ratios (SIR) for total and site-specific cancers among 14 088 patients with a primary diagnosis of Parkinson's disease, 1977–1998

From: Atypical cancer pattern in patients with Parkinson's disease

Site of cancer (ICD-7)

No. observed

No. expected

SIR

95% CI

All sites combined (140–205)

1282

1463.9

0.88

0.8–0.9

 Melanoma of skin (190)

44

22.5

1.95

1.4–2.6

 Other skin (191)

292

234.4

1.25

1.1–1.4

All sites except skin

990

1229.5

0.81

0.8–0.9

 Breast

142

114.6

1.24

1.0–1.5

All sites except skin and breast

804

1092.4

0.74

0.7–0.8

All smoking-related sites

285

491.3

0.58

0.5–0.6

 Lung (162.0–1)

66

174.8

0.38

0.3–0.5

 Larynx (161)

5

10.7

0.47

0.2–1.1

 Urinary bladder (181)

50

95.3

0.52

0.4–0.7

 Buccal cav., pharynx (140–148)

15

24.6

0.61

0.3–1.0

 Esophagus (150)

10

15.2

0.66

0.3–1.2

 Myeloid leukaemia (204, partly)

10

14.4

0.69

0.3–1.3

 Liver

10

14.4

0.70

0.3–1.3

 Cervix uteri (171)

10

13.1

0.76

0.4–1.4

 Stomach (151)

39

47.0

0.83

0.6–1.1

 Pancreas (157)

37

44.6

0.83

0.6–1.1

 Kidney (180)

33

37.2

0.89

0.6–1.3

Other specified sites

422

521.3

0.81

0.7–0.9

 Gallbladder

9

14.5

0.62

0.3–1.2

 Ovary (175)

15

23.3

0.64

0.4–1.1

 Multiple myeloma (203)

12

17.3

0.69

0.4–1.2

 Other leukaemias (204, partly)

16

22.4

0.71

0.4–1.2

 Prostate (177)

90

121.9

0.74

0.6–0.9

 Non-Hodgkin's lymphoma (200, 202)

23

30.0

0.77

0.5–1.2

 Colon (153)

120

142.2

0.84

0.7–1.0

 Endometrium (172)

23

26.6

0.87

0.6–1.3

 Rectum (154)

63

70.5

0.89

0.7–1.1

 Brain (193)

31

23.5

1.32

0.9–1.9

 Remaining specified sites

20

29.1

0.69

0.4–1.1

Secondary and unspecified sites

97

80.1

1.21

1.0–1.5