Table 2 Frequency and median levels of survivin, survivin-2B and survivin-ΔEx3 mRNA in normal breast tissue, fibroadenomas, primary breast cancer and axillary nodal metastases from breast cancer
From: Expression of survivin and its splice variants survivin-2B and survivin-ΔEx3 in breast cancer
Survivin | Survivin-2B | Survivin-ΔEx3 | ||||
|---|---|---|---|---|---|---|
Tissue | No. positive (%) | Median level | No. positive (%) | Median level | No. positive (%) | Median level |
Normal breast (n=22) | 5 (22.7) | 0 | 1 (4.5) | 0 | 1 (4.5) | 0 |
Fibroadenoma (n=31) | 21 (67.7) | 0.118 | 15 (48.4) | 0 | 16 (51.6) | 0 |
Primary breast carcinoma (n=156) | 146 (93.6) | 0.467 | 96 (61.5) | 0.041 | 86 (55.1) | 0.025 |
Nodal metastases (n=11) | 11 (100) | 0.509 | 9 (81.8) | 0.255 | 5 (45.5) | 0.197 |
