Table 3 Relationship between survivin, survivin-2B and survivin-ΔEx3 and established prognostic factors in breast cancer
From: Expression of survivin and its splice variants survivin-2B and survivin-ΔEx3 in breast cancer
Median levels (OD units/relative to GAPDH) | ||||
|---|---|---|---|---|
Characteristic | n | Survivin | Survivin-2B | Survivin-ΔEx3 |
Size (cm) | ||||
⩽2 | 34 | 0.488 | 0.096 | 0.134 |
>2 | 114 | 0.523 | 0.110 | 0.142 |
Nodal status | ||||
Positive | 85 | 0.490 | 0.113 | 0.118 |
Negative | 63 | 0.534 | 0.103 | 0.157 |
Histology | ||||
Ductal(D) | 115 | 0.549 | 0.112 | 0.146* |
Lobular (L) | 25 | 0.386 | 0.075 | 0.084 |
Mixed D+L | 11 | 0.405 | 0.114 | 0.159 |
Grade | ||||
1+2 | 57 | 0.495 | 0.104 | 0.133 |
3 | 77 | 0.568 | 0.124 | 0.154 |
ER status | ||||
Positive | 102 | 0.508 | 0.108 | 0.146 |
Negative | 41 | 0.519 | 0.111 | 0.146 |
PR status | ||||
Positive | 56 | 0.503 | 0.089 | 0.143 |
Negative | 90 | 0.525 | 0.125 | 0.154 |
