Figure 6 | British Journal of Cancer

Figure 6

From: Validation of pharmacodynamic assays to evaluate the clinical efficacy of an antisense compound (AEG 35156) targeted to the X-linked inhibitor of apoptosis protein XIAP

Figure 6

Effect of the treatment of MDA-MB-231/X-G4 cells with staurosporine plus or minus the general caspase inhibitor zVAD on the levels of CK18-asp396 NE antigen detected in the culture medium by the M30 Apoptosense Elisa assay. Cells were incubated for 24 h with either 10 or 100 nM staurosporine (Stauro, S) in the presence or absence of 50 μ M zVAD. Each bar represents the mean value±s.d., n=3.

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