Table 3 Allele frequency distribution of polymorphic genetic variants by breast cancer status at follow-up

From: Insulin-like growth factor-1 (IGF1) genotype predicts breast volume after pregnancy and hormonal contraception and is associated with circulating IGF-1 levels: implications for risk of early-onset breast cancer in young women from hereditary breast cancer families

IGF1 genotype

All women ( n =254)

No breast cancer ( n =248)

Breast cancer ( n =6)

(VNTR)

No. (%)

No. (%)

No. (%)

12

3 (0.6%)

2 (0.4%)

1 (8.3%)

13

14

15

16

17

8 (1.6%)

8 (1.6%)

18

32 (6.3%)

32 (6.5%)

19

333 (65.6%)

330 (66.5%)

3 (25.0%)

20

91(17.9%)

87 (17.5%)

4 (33.3%)

21

35 (6.9%)

32 (6.5%)

3 (25.0%)

22

6 (1.2%)

5 (1.0%)

1 (8.3%)

IGF1 19-repeat allele

 Absent

33 (13.0%)

29 (11.7%)

4 (66.7%)

 Present

221 (87.0%)

219 (88.3%)

2 (33.3%)

  1. Genotype was missing for four women without breast cancer.