Figure 2 | British Journal of Cancer

Figure 2

From: MET signalling in primary colon epithelial cells leads to increased transformation irrespective of aberrant Wnt signalling

Figure 2

There is no active Wnt signalling in the fetal colon epithelial cells. TOPflash and FOPflash activities were measured in colon epithelial cells containing empty vector, WTMet or Metmut constructs. As a positive control for active Wnt signalling, TOPflash and FOPflash activities were also measured in DLD1 cells. Measurements were corrected for differences in transfection efficiency using a Renilla luciferase-encoded construct.

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