Table 1 Patient characteristics

From: Phase I/II study of oral etoposide plus GM-CSF as second-line chemotherapy in platinum-pretreated patients with advanced ovarian cancer

Number of patients (n)

18

Age (years) median (range)

58 (43–72)

Sites of metastases

 

 One site

9

 Two sites

8

 Three sites

1

Tumour grade (n)

 

 Well differentiated

1

 Moderately differentiated

5

 Poorly or undifferentiated

12

Performance status according to Karnofsky (%)

 

 70

1

 80

8

 90

4

 100

4

 NE

1

Time (months) elapsing from last platinum dose to start of oral etoposide

 

 Median (range)

10 (1–24)

Previous chemotherapy as first-line therapy (no. of patients)

 

 Platinum based

18

 Cyclophosphamide

9

 Epidoxorubicin

1

 Paclitaxel

5

Response to previous platinum (no. of patients)

 

 Platinum sensitive

9

 Platinum resistant

9

  1. NE=not evaluable.