Table 4 Number of patients (n=18) with nonhaematological toxicities (World Health Organization (WHO) grade) over all cycles

From: Phase I/II study of oral etoposide plus GM-CSF as second-line chemotherapy in platinum-pretreated patients with advanced ovarian cancer

 

WHO grade

Toxicity

0

1

2

3

4

Nausea/vomiting

5

2

7

4

0

Mucositis

9

6

3

0

0

Diarrhoea

9

2

5

1

1

Constipation

11

1

6

0

0

Infection

9

6

1

1

1

Alopecia

0

0

2

16

0

Skin

12

5

1

0

0

Paraesthesia

17

1

0

0

0

Lethargy

16

2

0

0

0

GOT

16

2

0

0

0

Bilirubin

17

1

0

0

0

Creatinine

17

0

1

0

0

Alkaline phosphatase

16

2

0

0

0

  1. GOT=glutamate oxaloacetic transaminase (U l−1), alkaline phosphatase (U l−1), bilirubin (mg %−1), creatinine (mg %−1).
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