Table 7 Relationship of response to oral etoposide and sequence of chemotherapy in patients with advanced ovarian cancer

From: Phase I/II study of oral etoposide plus GM-CSF as second-line chemotherapy in platinum-pretreated patients with advanced ovarian cancer

     

Grouped according to line of therapy

Author

Line of therapy

Patients in each study ( n)

Responding patients ( n)

Response rate (%)

Patients ( n)

Responding patients ( n)

Response rate (%)

Tuxen et al (1997)

1

21

10

48

   
     

21

10

48

Maskens et al (1981)

2

18

0

0

   

Yasumizu and Kato (1995)

2

14

6

43

   

Kuhn et al (1996)

2

18

4

22

   

Rose et al (1998)

2

82

25

31

   

Hoskins and Swenerton (1994)

2

31

8

26

   

Baur et al

2

16

7

44

   
     

179

50

28

Markman et al (1992)

3

18

1

6

   

Garrow et al (1992)

3

15

3

20

   

Alici et al (2003)

2,3

22

4

18

   

Hansen et al (1990)

2,3

20

2

10

   

Seymour et al (1994)

2,3

41

10

24

   

De Wit et al (1994)

2,3

25

4

16

   

Hillcoat et al (1985)

2,3,4

23

5

22

   

Marzola et al 1993

3,4

17

1

6

   
     

181

30

17

Kavanagh et al (1995)

5

14

0

0

   
     

14

0

0

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