Figure 3

Effect of As-ODN and wortmannin on radiation-induced Rad51 foci in A549 and H460. Cells were transfected with lipofectamin only (L), UR ODN, sense- (S-Rad51) or antisense-ODN targeting Rad51 (As-Rad51), and treated with 20 μ M wortmannin (W20) or DMSO (W0) 1 h before irradiation with 10 Gy. Cells were fixed for foci evaluation at 4 h after irradiation.