Table 3 Clinicopathologic features and hDAB2IP promoter methylation in gastric cancer

From: Aberrant promoter methylation in human DAB2 interactive protein (hDAB2IP) gene in gastrointestinal tumour

Clinicopathologic features

Variable a

Frequency of hDAB2IP m2a methylation (%)

P -value b

Frequency of hDAB2IP m2b methylation (%)

P -value b

Sex

Male (n=21)

8 (38)

0.27

9 (43)

>0.99

 

Female (n=14)

8 (57)

 

6 (43)

 

Tumour invasion

T1, 2 (n=20)

9 (45)

0.92

9 (45)

0.77

 

T3, 4 (n=15)

7 (47)

 

6 (40)

 

Nodal metastasis

N0 (n=14)

7 (50)

0.68

7 (50)

0.49

 

N1, 2 (n=21)

9 (43)

 

8 (38)

 

Metastasis

M0 (n=26)

12 (46)

0.93

11 (42)

0.91

 

M1 (n=9)

4 (44)

 

4 (44)

 

TNM stage

1, 2 (n=18)

8 (44)

0.88

8 (44)

0.85

 

3, 4 (n=17)

8 (47)

 

7 (41)

 

Histology

Intestinal (n=17)

8 (47)

0.88

6 (35)

0.38

 

Diffuse (n=18)

8 (44)

 

9 (50)

 

Tumour site

U (n=7)

2 (22)

0.017

1 (14)

0.0064

 

M (n=13)

3 (23)

 

3 (23)

 
 

L (n=15)

11 (73)

 

11 (73)

 
  1. aU=upper site; M=middle site; L=lower site.
  2. bStatistical significance was determined using χ2 test.