Table 4 Clinicopathologic features and hDAB2IP promoter methylation in colorectal cancer
Clinicopathologic features | Variable a | Frequency of hDAB2IP m2a methylation (%) | P -value b | Frequency of hDAB2IP m2b methylation (%) | P -value b |
|---|---|---|---|---|---|
Sex | Male (n=37) | 18 (49) | 0.95 | 15 (41) | 0.23 |
Female (n=23) | 11 (48) | 13 (57) | |||
Tumour invasion | T1, 2 (n=9) | 4 (44) | 0.80 | 5 (56) | 0.56 |
T3, 4 (n=51) | 25 (49) | 23 (45) | |||
Nodal metastasis | N0 (n=25) | 9 (36) | 0.11 | 11 (44) | 0.73 |
N1, 2 (n=35) | 20 (57) | 17 (49) | |||
Metastasis | M0 (n=53) | 26 (49) | 0.76 | 25 (47) | 0.83 |
M1 (n=7) | 3 (43) | 3 (43) | |||
TNM stage | 1, 2 (n=21) | 7 (33) | 0.088 | 9 (43) | 0.66 |
3, 4 (n=39) | 22 (56) | 19 (49) | |||
Histological grade | G1 (n=13) | 7 (54) | 0.65 | 6 (46) | 0.97 |
G2, 3, 4 (n=47) | 22 (47) | 22 (47) | |||
Tumour site | C, A, T (n=12) | 4 (33) | 0.25 | 3 (25) | 0.093 |
D, S, R (n=48) | 25 (52) | 25 (52) |
