Table 4 Presence or absence of lung cancer in relatives of probands and relatives of spouses

Relative	Lung cancer presence	Proband	Spouse	OR1 ^a	95% CI	OR2 ^b	95% CI
Father	Yes	43	20	2.22^*	1.26–3.95	2.17^**	1.21–3.86
	No	697	720
Mother	Yes	50	15	3.50^*	1.89–6.58	3.78^*	2.03–7.12
	No	690	725
Parent	Yes	93	35	2.77^*	1.83–4.19	2.90^*	1.97–4.32
	No	1387	1445
Brother	Yes	61	47	1.23	0.82–1.86	1.21	0.79–1.80
	No	935	889
Sister	Yes	55	27	2.07^*	1.26–3.42	2.23^*	1.46–4.00
	No	581	591
Sibling	Yes	116	74	1.53^*	1.12–2.09	1.65^**	1.19–2.18
	No	1516	1480
Male^c	Yes	104	67	1.53^*	1.10–2.12	1.33^**	1.02–2.02
	No	1632	1609
Female	Yes	105	42	2.59^*	1.77–3.80	2.67^*	1.90–3.94
	No	1271	1316
Total	Yes	209	109	1.93^*	1.51–2.47	2.05^*	1.68–2.53
	No	2903	2925

OR=odds ratio; CI=confidence interval.
^*P<0.01.
^**P<0.05.
^aOR1, estimate of lung cancer for relatives of probands vs relatives of spouses, not adjusted.
^bOR2, estimate of lung cancer for relatives of probands vs relatives of spouses, adjusted for age, sex, birth order, size of the family, commune of residence, COPD, smoking and cumulation index of smoky coal exposure.
^cFathers and brothers.

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