Table 1 Clinicopathologic features of the patients

From: Phase II study of weekly vinorelbine and 24-h infusion of high-dose 5-fluorouracil plus leucovorin as first-line treatment of advanced breast cancer

 

Patient number

Total patients

40

Age, median (range)

49 (36–68)

ECOG performance:

 0

10 (25.0%)

 1

24 (60.0%)

 2

6 (15.0%)

Menopausal status

 Premenopause

18 (45.0%)

 Postmenopause

22 (55.0%)

Oestrogen receptor status

 Positive

21 (52.5%)

 Negative

11 (27.5%)

 Unknown

8 (20.0%)

Disease status

 Recurrence/metastasis

25 (62.5%)

de novo metastasis

15 (37.5%)

Prior therapy

 Anthracycline-containing adjuvant chemotherapy

15 (37.5%)

 CMF adjuvant chemotherapy

2 (5.0%)

 Hormonal therapy

21 (52.5%)

 Local radiotherapy

11 (27.5%)

Disease sites

 Lymph nodes

33 (82.5%)

 Lung

26 (65.0%)

 Breast

19 (47.5%)

 Bone or/and spine

16 (40.0%)

 Liver

12 (30.0%)

 Pleural effusion

8 (20.0%)

 Skin

6 (15.0%)

 Others

1 (2.5%)