Figure 2 | British Journal of Cancer

Figure 2

From: A modified Trastuzumab antibody for the immunohistochemical detection of HER-2 overexpression in breast cancer

Figure 2

BiotHER immunostaining is restricted to membranes of (A) BT474 cells and of (B) cancer cells in paraffin-embedded tumour samples; (C) no background or (D) normal cell staining is observed. (E) BiotHER stains amplified tumour cells (F) (CISH; large gene copy cluster/nucleus), and (E, F arrows) is negative in normal nonamplified residual cells (two signals/nucleus).

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