Table 4 No. (%) of cases and controls positive for HPV 16 and HPV 18 along with results from logistic regression analysis

From: Human papillomavirus infection in women who develop high-grade cervical intraepithelial neoplasia or cervical cancer: a case–control study in the UK

 

Cases HPV+

Controls HPV+

OR a (95% CI)

Age group at baseline

N (%)

N (%)

Model 1 b

Model 2 c

HPV 16

 Under 20

9 (9.3)

5 (5.0)

2.25 (0.71–7.13)

2.10 (0.61–7.30)

 20–39

39 (14.6)

10 (3.8)

4.62 (2.24–9.51)

4.15 (1.99–8.64)

 40 or over

22 (11.0)

3 (1.4)

8.95 (2.63–30.4)

9.08 (2.65–31.1)

 All ages

70 (12.4)

18 (3.1)

4.48 (2.61–7.55)

4.18 (2.44–7.18)

HPV 18

 Under 20

3 (3.1)

3 (3.0)

1.12 (0.22–5.78)

0.85 (0.15–4.95)

 20–39

12 (4.6)

6 (2.3)

2.02 (0.74–5.49)

2.15 (0.72–6.44)

 40 or over

12 (6.0)

8 (3.6)

1.69 (0.68–4.23)

1.30 (0.49–3.48)

 All ages

27 (4.8)

17 (2.9)

1.72 (0.93–3.20)

1.48 (0.77–2.86)

  1. HPV=human papillomavirus; OR=odds ratio; CI=confidence interval.
  2. aFor cases vs controls (logistic regression).
  3. bAdjusted for age in years.
  4. Adjusted for age in years, infection with other specific HPV type (16 or 18) and infection with unknown HPV type (positive using GP5+/6+ primers but negative for HPV 16/18).
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