Figure 5
Time-lapse recording of cell migration in UB09 cells after transfection of RON. The cells (5 × 105) were plated on a 1-cm cover slide and grown for 1 day, during which the cells formed a monolayer. Cells were then wounded with a yellow tip. The healing of the wounds was recorded every 20 min for a total of 20 h. (A) Distance of wounding of UB09/RON and UB09 cells, respectively. (B) Quantitative data of migration distance for UB09/RON and UB09 cells, respectively. Overexpression of RON increased the migration distance, symbolic for cell motility, of cancer cells (P=0.04, t-test).
