Table 1 Distribution of RON and MET expression, and biological indicators

From: Co-expression of RON and MET is a prognostic indicator for patients with transitional-cell carcinoma of the bladder

 

RON

MET

Clinical characteristics

Positive (%)

Negative (%)

P -value

Positive (%)

Negative (%)

P-value

Histological grade

 Grade I

2 (1.1)

20 (10.9)

0.003

4 (2.2)

18 (9.8)

<0.0001

 Grade II

22 (12.0)

58 (31.7)

 

25 (13.7)

55 (30.1)

 

 Grade III

36 (19.7)

45 (24.6)

 

83 (45.4)

28 (15.3)

 

Tumour shape

 Papillary

31 (16.9)

95 (51.9)

0.005

44 (24.0)

82 (44.8)

<0.0001

 Nonpapillary

29 (15.8)

28 (15.3)

 

38 (20.8)

19 (10.4)

 

Tumour size

 ⩽1 cm

5 (2.7)

31 (16.9)

0.003

8 (4.4)

28 (15.3)

0.0004

 >1 to ⩽3 cm

22 (12.0)

54 (29.5)

 

32 (17.5)

44 (24.0)

 

 >3 to ⩽5 cm

20 (10.9)

22 (12.0)

 

28 (15.3)

14 (7.7)

 

 >5 cm

10 (5.5)

7 (3.8)

 

11 (6.0)

6 (3.3)

 

 N/Aa

3 (1.6)

9 (4.9)

 

3 (1.6)

9 (4.9)

 

Multiplicity

 Single

28 (15.3)

86 (47.0)

0.37

60 (32.8)

64 (35.0)

0.16

 Multiple

22 (12.0)

37 (20.2)

 

22 (12.0)

37 (20.2)

 

Stage (TNM staging system)

 pTa

9 (4.9)

45 (24.6)

0.01

13 (7.1)

41 (22.4)

0.001

 pT1

9 (4.9)

30 (16.4)

 

17 (9.3)

22 (12.0)

 

 pT2a

16 (8.7)

17 (9.3)

 

23 (12.6)

10 (5.5)

 

 pT2b

5 (2.7)

7 (3.8)

 

5 (2.7)

7 (3.8)

 

 pT3

7 (3.8)

5 (2.7)

 

8 (4.4)

4 (2.2)

 

 pN1/pN2

8 (4.4)

11 (6.0)

 

13 (7.1)

6 (3.3)

 

 M+

2 (1.1)

2 (1.1)

 

2 (1.1)

2 (1.1)

 

 N/Aa

4 (2.2)

6 (3.3)

 

1 (0.5)

9 (4.9)

 
  1. CI=confidence interval. RON=Recepteur d'Origine Nantais. MET=c-met protein.
  2. aN/A: not applicable.