Figure 5
Effects of KP372-1 on the proliferation of thyroid carcinoma cell lines in vitro. (A, B) Thyroid carcinoma cell lines NPA187 and WRO were plated in six-well plates and treated with 30 and 60 nM KP372-1 for NPA187 and WRO cell lines, respectively, for 1, 2, or 3 days. Cell proliferation was then measured by cell counting using a haemacytometer. (C, D) Thyroid carcinoma cell lines NPA187 and WRO were plated in a 96-well plate and treated with various concentrations (0–120 nM) of KP372-1 for 48 h. Cell proliferation was then measured by 3H-thymidine incorporation. Results shown are representative of three experiments.
