Table 3 Distribution of Pedigrees of melanoma families without neural system tumours, by tumour type and family affiliation

From: Search for germline alterations in CDKN2A/ARF and CDK4 of 42 Jewish melanoma families with or without neural system tumours

 

Patient

Affected relatives

Family # (n =18)

DNA# ( n =20)

Gender

MM (a)

Additional cancers

MM

Additional cancers

   

(Age at diagnosis)

(Age at diagnosis)

302

104

F

74

Cousin (72)

303

103

M

49

(7 primary MM)

BCC

SCC

Brother

305

100

F

74

BCC (75)

Nephew

309

112

F

52

Pancreas (father)

310

111

F

45

64

311

105

F

48

Sister

Breast (mother)

312

119

M

68

Prostate (68)

Mother (83)

Brother (65)

Daughter (19)

317

116

F

60

Grandmother

319

114

M

36

Cousin

321

15

F

25

Grandfather (61)

Uncle

TCC (cousin)

Breast (grandmother)

322

124

M

66

Prostate

Breast (mother)

   

67

(67)

  

325

78

F

61

61

Breast (56)

 

79

F

33

daughter

  

327

121

M

86

 

135

F

88

sister

  

329

122

F

47

62

Lymphoma (mother)

330

140

F

67

71

Daughter

335

134

F

25

Breast

Uncle

Grandfather

Breast (mother)

BCC (father)

337

141

M

64

65

Prostate (56)

338

138

F

52

53

BCC (47)

Daughter (32)

  1. aMM=melanoma.