Table 2 Expressiona of ErbB family genes and von Hippel–Lindau (VHL) mutant status in renal cell carcinoma (RCC) cell lines

From: Synergistic growth inhibition by Iressa and Rapamycin is modulated by VHL mutations in renal cell carcinoma

Sample

EGFR

ErbB-2

ErbB-3

ErbB-4

VHL mutation

VHL exp.

PV10

0.3

0

0.003

0

NDb

 

KRCY

0.6

0

0.028

0

Wt

0.3

SKRC39

0.8

0.018

0.009

0.030

Wt

1.2

KV6

1.8

0

0.0004

0

Wt

0.01

A498

2.0

0

0.002

0.002

V142/D143-f.s.c

 

ACHN

2.2

0.002

0.142

0

Wtd

0.2

SKRC48

4.3

0

0.006

0.001

L135-f.s.

 

SKRC12

4.5

0

0.009

0

N121Y

 

CAKI2

4.7

0.002

0.309

0

ND

 

A704

5.8

0.001

0.303

0

ND

 

SKRC17

6.3

0.003

0.002

0.001

S68->stop

 

SKRC02

8.0

0.001

0.001

0

S68P

 

PRC3

9.3

0.002

0.002

0.010

ΔG104-f.s.

 

SKRC45

15.1

0.005

0.059

0

R82P

 
  1. Expressed as % of GAPDH.
  2. bNot determined.
  3. cf.s.=frameshift.
  4. dDiffers from lit report.