Table 4 mRNAa loading on polysomes in WT8 cells

From: Synergistic growth inhibition by Iressa and Rapamycin is modulated by VHL mutations in renal cell carcinoma

Gene

Treatment

1–2 rib

3–4 rib

Polyrib

MYC

DMSO

0.20

0.16

0.08

 

Iressa

0.11

0.09

0.09

 

Rapamycin

0.40

0.23

0.20

 

Iressa+Rapamycin

0.36

0.47

0.14

MYC

DMSO

0.31

0.42

0.24

 

LY294002

0.05

0.16

0.15

 

Ly+Rap

0.05

0.07

0.09

 

Ly+Rap+Iressa

0.03

0.05

0.09

RPS19

DMSO

319.3

117.7

10.6

 

Iressa

149.0

33.9

4.5

 

Rapamycin

199.3

32.9

3.3

 

Iressa+Rapamycin

101.4

52.5

2.6

  1. Expressed as % β-actin.
  2. DMSO=dimethyl sulphoxide.
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