Figure 3 | British Journal of Cancer

Figure 3

From: The endothelin B (ETB) receptor agonist IRL 1620 is highly vasoconstrictive in two syngeneic rat tumour lines: potential for selective tumour blood flow modification

Figure 3

Time course of relative blood flow changes in P22 tumour and normal tissues of BDIX rats following i.v. administration of IRL 1620 at a dose of 3 nmol kg−1 plotted as % of the value in time-matched saline-treated rats. Each time point represents arithmetic mean±s.e. for three to six animals. P-values represent significance levels for statistical comparisons of curves obtained from drug-treated and saline-treated rats (see Materials and Methods for details).

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