Table 1 Effects of anti-oestrogen therapy on plasma lipid levels (Dewar et al, 2000; Nicolaides et al, 2000; Elisaf et al, 2001; Goss et al, 2001, 2003; Harper-Wynne et al, 2001; ATAC, 2002; Kataja et al, 2002; Boccardo et al, 2003; Markopoulos et al, 2003; Sawada and Sato, 2003; Atalay et al, 2004; Coombes et al, 2004; Hozumi et al, 2004; Paridaens et al, 2004; Wojtacki et al, 2004)
From: The effects of aromatase inhibitors on lipids and thrombosis
LDL cholesterol | HDL cholesterol | Total cholesterol | Triglycerides | Total : HDL cholesterol | Lp(a) | Apo B | |
|---|---|---|---|---|---|---|---|
Tamoxifen | ↓ | − | ↓ | ? | ? | ↓ | ↓ |
Anastrozole | ↑− | ↑/− | ↑/− | − | − | ↑/− | ↑/− |
Letrozole | ↑/− | − | ↑/− | − | ↑/− | ? | ↑/− |
Exemestane | ↓− | ↓/− | ↓/− | ↓ | ? | − | − |
