Table 2 Multivariate Cox's model of independent prognostic factors for survival in metastatic melanoma

From: Elevated neutrophil and monocyte counts in peripheral blood are associated with poor survival in patients with metastatic melanoma: a prognostic model

  

Multivariate Cox's analysis a

 

Risk factors

Categories compared

Hazard ratio

95% CI

P -value

Regression coefficients

Weight (contribution to cumulative risk score)

Performance status

0–1 vs 2

1.6

1.1–2.3

0.008

0.47

0 vs 1

LDH

Normal vs elevated

2.8

2.2–3.6

<0.001

1.03

0 vs 2

Neutrophils

Normal vs elevated

1.4

1.1–1.8

0.02

0.32

0 vs 1

  1. CI=confidence interval; LDH=lactate dehydrogenase. All other variables (location of metastases, number of metastatic sites and blood monocytes) were not significant and therefore excluded from the model.
  2. aIn all, 320 patients and 301 deaths. Analysis stratified by treatment regimen.
Back to article page