Table 2 Characteristics of women who opted for CPM and women under surveillance
Characteristic | CPM group ( N =79) | Surveillance group ( N =69) | P -value |
|---|---|---|---|
Mutation status, N (%) | 0.693 | ||
BRCA1 | 60 (75.9) | 55 (79.7) | |
BRCA2 | 19 (24.1) | 14 (20.3) | |
Age at mutation analysis (years) | |||
Mean±s.e. | 41.5±0.9 | 46.7±1.1 | <0.001 |
Range | 27–61 | 26–76 | |
Age at CPM (years) | |||
Mean±s.e. | 41.9±0.9 | NA | |
Range | 27–61 | NA | |
Bilateral (salpingo-)oophorectomy, N (%) | 63 (79.7) | 46 (66.7) | 0.092 |
Indication | |||
Prophylactic | 61 (96.8) | 39 (84.8) | 0.009a |
Ovarian carcinoma | 2 (3.2) | 4 (8.7) | |
Metastasis breast cancer in ovary | — (0.0) | 1 (2.2) | |
Adjuvant treatment first breast cancer | — (0.0) | 1 (2.2) | |
Radiologic castration | — (0.0) | 1 (2.2) | |
Age at bilateral prophylactic (salpingo-)oophorectomy (years) | |||
Mean±s.e. | 43.3±0.8 | 47.1±1.2 | 0.009 |
Range | 30–60 | 35–64 | |
Ipsilateral mastectomy (before or at the start of follow-up) | 79 (100) | 34 (49.3) | <0.001 |
