Figure 7

Histological and immunohistochemical analyses of AsPC-1 tumours treated with AxCA-IFN and AdCA-mIFN. At 5 days after the injection of 1.0 × 108 PFU of viral solutions, the subcutaneous tumours were fixed with formalin for haematoxylin-eosin (HE) staining, immunohistochemistry with anti-asialo GM1 antibody or TUNEL staining (× 200). Fresh tumour samples were embedded in OCT compound and sections were fixed with 4% paraformaldehyde and then processed for immunohistochemistry with anti-mouse CD31 antibody (× 200).