Figure 10
(A) Chemotherapeutic effect of gemcitabine 120 mg kg−1 i.p. four times at 3-day intervals and fluvastatin 30 mg kg−1 i.p. every 2 days alone or in combination on MIAPaCa-2 tumours xenotransplanted in CD nu/nu mice. *P<0.05 with respect to controls; **P<0.05 vs gemcitabine and fluvastatin alone. Symbols and bars, mean±s.e. (B) Body weight of MIAPaCa-2 tumour-bearing control mice and mice treated with gemcitabine and fluvastatin alone or in combination. No changes or decline in body weight were noted. Symbols and bars, mean±s.e.
