Figure 3 | British Journal of Cancer

Figure 3

From: Angiotensin II directly induces muscle protein catabolism through the ubiquitin–proteasome proteolytic pathway and may play a role in cancer cachexia

Figure 3

Western blots for the effect of Ang I on the expression of 20S proteasome α-subunits (A), p42 (B) and myosin (D) in soluble extracts of C2C12 myotubes after 24 h incubation alone or in the presence of imidaprilat (50 μ M). An actin loading control is shown in (C) and (E), and a densitometric analysis of three separate blots is shown underneath. Differences from control are shown as c, P<0.001, while differences in the presence of inhibitors are shown as d, P<0.05, e, P<0.01 or f, P<0.001.

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