Table 4 Odds ratios (OR), 95% confidence intervals (CI) and numbers of exposed cases (ca) and controls (co) for risk factors for HL patients only

Factor	Category ^a	HL patients univariate OR (95% CI) ca 35, co 70	HL patients multivariate OR (95% CI)
Decade of diagnosis (years)	1970–1979	1.00	1.00
		24, 40
	1980–1989	0.45 (0.11–1.78)	0.31 (0.06, 1.56)
		11, 25
	1990–1999	—	—
		0, 5
Stage at diagnosis	Low	1.00	1.00
		26, 47
	High	0.73 (0.31–1.73)	1.26 (0.33–4.74)
		9, 23
Presenting site at diagnosis	Nodal disease	1.00	1.00
		34, 62
	Extra-nodal disease	—	—
		0, 2
	Other	—	—
		1, 6
Treatment given	RT only	1.00	1.00
		18, 28
	CT only	0.53 (0.18–1.55)	0.66 (0.13–3.28)
		7, 20
	RT and CT	0.65 (0.22–1.95)	0.55 (0.16–1.89)
		9, 22
	Surgery only/no treatment/treatment u/k	—	—
		1, 0
Histology	Nodular sclerosing	1.00	1.00
		13, 20
	Mixed cell	0.73 (0.29–1.87)	0.69 (0.25–1.88)
		14, 30
	Other HL	0.63 (0.22–1.80)	0.65 (0.22–1.95)
		8, 20
Splenectomy	No	1.00	1.00
		23, 51
	Yes	1.48 (0.57–3.79)	1.51 (0.50–4.56)
		12, 19

^aReference category stated first.
—, odds ratio not presented as fewer than 5% of either cases or controls in the risk factor level.

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