Figure 4
Correlation of the expression of IIRK, IhERG, IhELK2 and the corresponding transcripts with tumour grade, in primary gliomas. Bars represent the percentage of cases expressing the indicated K+ current (white bars), or the corresponding transcript (black bars), among the indicated tumour classes. Data were obtained by patch-clamp for K+ currents and RT–PCR for transcript expression (see text). Panels A–C show the results obtained for IIRK/Kir 2.1, IhERG/herg1 and IhELK2/helk2, respectively. Controls: normal cases; AI–III: astrocytoma WHO grade I–III; GBM: glioblastoma multiforme, WHO grade IV; OD: oligodendroglioma; OA: oligoastrocytoma; Ep: ependimoma.
