Table 3 Effect of WAY on Vrest of U138 and A172 glioma cells

From: hERG1 channels are overexpressed in glioblastoma multiforme and modulate VEGF secretion in glioblastoma cell lines

Cell line

V rest (mV) Control conditions

V rest (mV) (1  μ M WAY)

V rest (mV) (40  μ M WAY)

U138

−18±3 (7)

−12±2 (7)

−6±2 (7)

A172

−22±2 (7)

−24±1 (7)

−22±2 (7)

  1. Vrest and its variation after application of 1 and 40 μ M WAY were determined as reported in Materials and Methods. Values are means±s.e.m.; cell count is reported in parentheses.