Table 1 Expression data and sample details: Patients are ranked according to the comparative multiplex RT-PCR values for AURKB (column 2)

From: Overexpression of aurora B kinase (AURKB) in primary non-small cell lung carcinoma is frequent, generally driven from one allele, and correlates with the level of genetic instability

 

Aurora B

Aurora A

   

Patient

cmRT-PCR

Real time

Real time

Gender

Age

Tumour type

195

0.3

0.4

37

M

65.4

Squamous cell

179

0.8

1

0.9

M

47.8

Squamous cell

187

1

1

 

F

51.8

Adeno

206

2

1

0.6

M

59.5

Squamous cell

210

2

5

23

M

52.6

Adeno

223

2

5

6

M

67.2

Adeno

173

3

2

50

M

73.4

Adeno

182

4

4

9

M

69.5

Squamous cell

176

4

5

2

F

57.4

Adeno

231

6

17

0.07

M

72.5

NSCLC

232

6

7

0.5

M

74.3

Adeno

184

6

3

8

F

39.2

Adeno

211

6.8

1

2

M

71.5

Adeno

208

7

4

6

M

47.6

Squamous cell

205

8

11

3

M

73.3

Squamous cell

216

8

10

6

M

57.7

Squamous cell

217

9

11

 

F

69.5

Adeno

237

12

12

 

M

79.5

Squamous cell

224

13

19

 

M

68.5

Squamous cell

222

13

21

 

M

54.6

Adeno

226

14

16

 

F

62.6

Adeno

186

15

14

 

M

68.5

Adeno

227

16

17

 

M

74.8

Squamous cell

214

16

39

 

F

69.7

Adeno

236

17

20

 

F

80.6

Adeno

189

17

17

 

F

57.1

Adeno

233

18

18

 

F

50.4

Adeno

218

19

18

 

M

72

Adeno

235

27

42

0.001

M

65.6

Large cell

198

28

29

65

M

74.6

Squamous cell

194

29

14

14

M

68.9

Squamous cell

229

29

16

0.1

M

80.7

Adeno

193

30

21

7

M

74.8

Squamous cell

200

32

42

34

M

62.6

Adeno

207

36

721

2589

M

63.3

Squamous cell

183

40

53

25

M

63.7

Adeno

174

42

65

40

M

49.6

LCNEC

209

44

30

125

M

55.7

Squamous cell

204

47

81

22

M

58

Squamous cell

197

64

25

14

M

54.7

Squamous cell

230

76

108

40

M

70.1

Squamous cell

220

80

105

12

M

76.2

Squamous cell

175

144

85

—

F

65.2

Adeno

196

189

53

7

M

52.9

Adeno

  1. The corresponding real time values are listed in column 3 and the AURKA real time data for the two groups analysed for genetic stability are given in column 4. Values are fold-change in the tumour relative to patient matched normal tissue, normalised by APPBP2 levels.
Back to article page