Table 4 Drug-related adverse events
Arm A ( n =50) | Arm B ( n =51) | |||
|---|---|---|---|---|
G1/2 | G3 | G1/2 | G3 | |
No. (%) | No. (%) | No. (%) | No. (%) | |
Leukopenia | 17 (34) | 3 (6) | 20 (39) | 3 (6) |
Neutropenia | 12 (24) | 11 (22) | 4 (8) | |
Thrombocytepenia | 9 (18) | 9 (18) | ||
Anaemia | 13 (26) | 17 (33) | 1 (2) | |
Elevation of Bilirubin | 7 (14) | 7 (14) | 2 (4) | |
Elevation of ALT, AST | 7 (14) | 8 (16) | 1 (2) | |
Anorexia | 14 (28) | 14 (27) | ||
Nausea and vomiting | 7 (14) | 15 (29) | ||
Diarrhoea | 4 (8) | 1 (2) | 12 (24) | 2 (4) |
Stomatitis | 6 (12) | 3 (6) | 1 (2) | |
Other GI toxicity | 3 (6) | 2 (4) | ||
Cutaneous symptoms | 9 (18) | 19 (37) | ||
Peripheral neuropathy | 1 (2) | 2 (4) | ||
Dizziness | 2 (4) | 1 (2) | 2 (4) | |
General fatigue | 10 (20) | 6 (12) | ||
Others | 8 (16) | 2 (4) | ||
