Table 1 Doses of gemcitabine, cisplatin and tipifarnib and number of patients included per dose level
Dose level | Gemcitabine (mg m −2 ) days 1 and 8 | Cisplatin (mg m −2 ) day 1 | Tipifarnib (mg twice daily) days 1–7 | n |
|---|---|---|---|---|
1 | 750 | 75 | 100 | 4 |
2 | 750 | 75 | 200 | 11 |
3 | 1000 | 75 | 200 | 6 |
4 | 1000 | 100 | 200 | 7 |
5 | 1000 | 100 | 300 | 3 |
