Table 6 Objective response rates
CR | PR | CR+PR | PD | ||||
|---|---|---|---|---|---|---|---|
Group | No. of evaluable patients | No. | No. | No. | % | No. | % |
Phase I | |||||||
60N | 7 | 0 | 1 | 1 | 14.3 | 2 | 28.6 |
60P | 5 | 0 | 1 | 1 | 20.0 | 2 | 40.0 |
65P | 4 | 0 | 3 | 3 | 75.0 | 0 | 0 |
70P | 3 | 0 | 0 | 0 | 0 | 1 | 33.3 |
75P | 6 | 1 | 3 | 4 | 66.0 | 0 | 0 |
80P | 2 | 0 | 1 | 1 | 50 | 0 | 0 |
Phase II | 48 | 0 | 30 | 30 | 62.5 (47.3–76.0)a | 7 | 14.6 (6.1–27.8) |
Total | 75 | 1 | 39 | 40 | 53.3 (41.4–64.9) | 12 | 16.0 (8.5–26.3) |
