Figure 1
From: The measurement and therapeutic implications of circulating tumour cells in breast cancer

Kaplan–Meier curves demonstrating differences in PFS (A and C) and OS (B and D) based upon high and low risk CTC classifications. Patients with elevated CTCs at baseline (A and B) and at first follow-up after one cycle of therapy (C and D) have significantly worse median PFS and OS compared to the corresponding patients with low CTCs. Adapted with permission from (Cristofanilli et al, 2004).