Table 2 Age-adjusted and multivariate RRs and 95% CI for ovarian cancer according to dairy consumption and intake of fat or lactose, Netherlands Cohort Study on Diet and Cancer, 1986–1997
From: Dairy consumption and ovarian cancer risk in the Netherlands Cohort Study on Diet and Cancer
All invasive epithelial ovarian tumours | Serous epithelial ovarian tumours | ||||||||
|---|---|---|---|---|---|---|---|---|---|
Median | Cases/person years a | RR (95% CI) a | Cases/person years b | RR (95% CI) b | Cases/person years a | RR (95% CI) a | Cases/person years b | RR (95% CI) b | |
Total milk (g day−1) | |||||||||
0 | 0 | 86/8021 | 1.00 | 75/7347 | 1.00 | 44/8021 | 1.00 | 39/7347 | 1.00 |
0.1–<66.0 | 60 | 36/3677 | 0.91 (0.61–1.37) | 33/3213 | 0.97 (0.63–1.50) | 14/3677 | 0.69 (0.37–1.28) | 12/3213 | 0.68 (0.35–1.32) |
66.0–<150.1 | 119 | 33/3048 | 1.01 (0.66–1.55) | 26/2733 | 0.95 (0.59–1.54) | 21/3048 | 1.26 (0.74–2.16) | 15/2733 | 1.04 (0.56–1.93) |
150.1–<186.0 | 171 | 53/4778 | 1.02 (0.71–1.46) | 49/4352 | 1.10 (0.75–1.62) | 28/4778 | 1.04 (0.64–1.70) | 26/4352 | 1.08 (0.64–1.81) |
⩾186.0 | 343 | 44/4269 | 0.96 (0.66–1.41) | 40/3849 | 0.98 (0.65–1.48) | 19/4269 | 0.81 (0.47–1.41) | 17/3849 | 0.79 (0.43–1.40) |
P-trend | 0.99 | 0.97 | 0.45 | 0.64 | |||||
Total yoghurt (g day−1) | |||||||||
0 | 0 | 69/6298 | 1.00 | 60/5677 | 1.00 | 37/6298 | 1.00 | 33/5677 | 1.00 |
0.1–<48.1 | 12 | 58/5507 | 1.00 (0.69–1.45) | 54/4939 | 1.07 (0.72–1.59) | 25/5507 | 0.80 (0.47–1.36) | 22/4939 | 0.77 (0.44–1.35) |
48.1–<96.2 | 53 | 58/4815 | 1.13 (0.78–1.64) | 52/4473 | 1.11 (0.74–1.65) | 34/4815 | 1.23 (0.76–1.99) | 31/4473 | 1.16 (0.69–1.94) |
⩾96.2 | 139 | 67/7174 | 0.88 (0.61–1.25) | 57/6406 | 0.87 (0.59–1.28) | 30/7174 | 0.73 (0.45–1.21) | 23/6406 | 0.60 (0.34–1.05) |
P-trend | 0.61 | 0.63 | 0.19 | 0.1 | |||||
Total cheese (g day−1) | |||||||||
0 | 0 | 18/1754 | 1.00 | 15/1597 | 1.00 | 10/1754 | 1.00 | 9/1597 | 1.00 |
0.1–<12.9 | 7 | 61/5812 | 1.01 (0.58–1.76) | 56/5160 | 1.21 (0.66–2.21) | 28/5812 | 0.83 (0.40–1.75) | 27/5160 | 0.93 (0.43–2.03) |
12.9–<18.6 | 19 | 60/6254 | 0.92 (0.52–1.60) | 53/5722 | 0.98 (0.53–1.81) | 32/6254 | 0.88 (0.43–1.83) | 26/5722 | 0.77 (0.35–1.69) |
18.6–<37.1 | 31 | 82/6953 | 1.13 (0.66–1.94) | 72/6297 | 1.20 (0.66–2.20) | 39/6953 | 0.96 (0.47–1.97) | 33/6297 | 0.86 (0.40–1.86) |
⩾37.1 | 56 | 31/3022 | 1.01 (0.55–1.86) | 27/2718 | 1.06 (0.54–2.08) | 17/3022 | 0.99 (0.45–2.22) | 14/2718 | 0.84 (0.35–2.03) |
P-trend | 0.85 | 0.8 | 0.97 | 0.96 | |||||
Fermented milk and milk products (g day−1) | |||||||||
0–<11 | 0 | 57/4759 | 1.00 | 52/4284 | 1.00 | 31/4759 | 1.00 | 28/4284 | 1.00 |
11–<53.4 | 28 | 49/4847 | 0.87 (0.58–1.30) | 44/4375 | 0.81 (0.53–1.25) | 20/4847 | 0.65 (0.36–1.15) | 18/4375 | 0.62 (0.34–1.16) |
53.4–<119.3 | 96 | 61/4745 | 1.10 (0.75–1.62) | 52/4276 | 1.01 (0.67–1.53) | 31/4745 | 1.02 (0.61–1.71) | 25/4276 | 0.89 (0.51–1.57) |
119.3–<192.7 | 144 | 43/4532 | 0.81 (0.53–1.23) | 38/4195 | 0.72 (0.46–1.13) | 22/4532 | 0.77 (0.44–1.34) | 18/4195 | 0.63 (0.34–1.15) |
⩾192.7 | 278 | 42/4911 | 0.74 (0.48–1.13) | 37/4365 | 0.67 (0.42–1.06) | 22/4911 | 0.71 (0.40–1.26) | 20/4365 | 0.64 (0.35–1.18) |
P-trend | 0.31 | 0.26 | 0.40 | 0.37 | |||||
Nonfermented milk and milk products (g day−1) | |||||||||
0–<46 | 21 | 45/4736 | 1.00 | 40/4359 | 1.00 | 24/4736 | 1.00 | 22/4359 | 1.00 |
46–<115.8 | 77 | 49/4688 | 1.11 (0.72–1.69) | 44/4158 | 1.16 (0.73–1.83) | 22/4688 | 0.92 (0.51–1.67) | 20/4158 | 0.93 (0.50–1.76) |
115.8–<192.7 | 155 | 50/4810 | 1.09 (0.72–1.67) | 42/4398 | 1.05 (0.66–1.67) | 32/4810 | 1.31 (0.76–2.26) | 25/4398 | 1.10 (0.60–2.02) |
192.7–<292.0 | 230 | 61/4811 | 1.32 (0.88–1.98) | 55/4337 | 1.32 (0.85–2.04) | 27/4811 | 1.07 (0.61–1.89) | 24/4337 | 1.01 (0.55–1.84) |
⩾292.0 | 375 | 47/4750 | 1.05 (0.68–1.61) | 42/4244 | 1.04 (0.65–1.65) | 21/4750 | 0.87 (0.48–1.58) | 18/4244 | 0.76 (0.40–1.47) |
P-trend | 0.71 | 0.70 | 0.63 | 0.85 | |||||
Dairy fat (g day−1) | |||||||||
0–<7.9 | 5 | 47/5191 | 1.00 | 43/4649 | 1.00 | 29/5191 | 1.00 | 28/4649 | 1.00 |
7.9–<12.7 | 10 | 49/5052 | 1.07 (0.70–1.63) | 44/4731 | 0.98 (0.63–1.53) | 26/5052 | 0.92 (0.53–1.58) | 23/4731 | 0.75 (0.42–1.33) |
12.7–<19.4 | 15 | 46/4776 | 1.07 (0.70–1.64) | 40/4256 | 1.00 (0.63–1.59) | 22/4776 | 0.82 (0.46–1.45) | 18/4256 | 0.64 (0.35–1.19) |
19.4–<31.0 | 24 | 46/4685 | 1.07 (0.70–1.64) | 40/4231 | 0.92 (0.58–1.47) | 24/4685 | 0.90 (0.52–1.56) | 20/4231 | 0.67 (0.37–1.22) |
⩾31.0 | 40 | 64/4091 | 1.70 (1.14–2.54) | 56/3628 | 1.53 (1.00–2.36) | 25/4091 | 1.04 (0.60–1.80) | 20/3628 | 0.76 (0.42–1.39) |
P-trend | 0.04 | 0.11 | 0.94 | 0.63 | |||||
Lactose (g day−1) | |||||||||
0–<7.7 | 5 | 59/4759 | 1.00 | 52/4310 | 1.00 | 29/4759 | 1.00 | 25/4310 | 1.00 |
7.7–<11.7 | 10 | 49/4824 | 0.82 (0.55–1.22) | 44/4393 | 0.87 (0.57–1.33) | 31/4824 | 1.06 (0.63–1.79) | 28/4393 | 1.11 (0.64–1.94) |
11.7–<15.6 | 14 | 39/4755 | 0.66 (0.43–1.01) | 33/4410 | 0.62 (0.39–0.98) | 16/4755 | 0.55 (0.30–1.03) | 12/4410 | 0.45 (0.22–0.91) |
15.6–<21.1 | 18 | 57/5196 | 0.89 (0.61–1.31) | 52/4620 | 0.92 (0.61–1.40) | 29/5196 | 0.92 (0.54–1.57) | 27/4620 | 0.95 (0.54–1.68) |
⩾21.1 | 26 | 48/4260 | 0.92 (0.61–1.38) | 42/3762 | 0.93 (0.60–1.45) | 21/4260 | 0.81 (0.46–1.45) | 17/3762 | 0.72 (0.37–1.38) |
P-trend | 0.41 | 0.32 | 0.29 | 0.11 | |||||
