Figure 4 | British Journal of Cancer

Figure 4

From: Mechanistic mathematical modelling of mercaptopurine effects on cell cycle of human acute lymphoblastic leukaemia cells

Figure 4

Molt-4 cell line. (A) Molt-4 sensitive cell line and (B) Molt-4 resistant cell line: -□- Control data. -♦- MP treated data. The solid line represents the model fit to the control data and the dashed line represents the model fit to the MP-treated data. Panel a: Total cell count vs time in hours. Panel b: Cell cycle distribution (fraction G0/G1, S, G2/M, respectively). Panel c: Cell viability distribution (i.e., fraction viable, fraction apoptotic, and fraction dead, respectively.

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