Figure 6

Pathway analysis of genes that changed expression before and after treatment with MP in resistant and in sensitive Molt-4 ALL cells. Arrows indicate genes discussed in the text. Forty-three probe sets (28 unique genes) were differentially expressed between resistant and sensitive Molt-4 ALL cells or changed expression before and after treatment with MP in resistant compared to sensitive Molt-4 ALL cells. These genes served as the input for the pathway query. Two networks were found that included the input genes (Network 1 shown in (A) and Network 2 in (B), respectively), genes labelled in green if expression decreased after MP treatment and red if expression increased after MP treatment and the number below the gene indicates the fold-change.