Table 1 Clinicopathological characteristics of patients with flat and depressed neoplasias, and protruding neoplasia

From: BRAF mutations and phosphorylation status of mitogen-activated protein kinases in the development of flat and depressed-type colorectal neoplasias

 

FDNs ( N =46)

PNs ( N =57)

P -value

Gender

 Male/female

34/10

34/16

0.3159*

 Mean age (year)

66.1

65.4

0.7001**

 (Range)

(41–85)

(32–82)

 

Family history of CRC

 Present

4

3

0.3158*

 Absent

35

45

 

 Unknown

5

2

 

Location

 Left-c and rectum

17

26

0.3575*

 Right-c

29

31

 

Size

 <10 mm

14

23

0.2970*

 ⩾10 mm

32

34

 

Macroscopic type

 Flat

27

NA

 

 Depressed

19

  

Histology

 Adenoma

29

44

0.1161*

 Dukes' A carcinoma

17

13

 

Accompanying adenoma in Dukes' A carcinoma

Present

4

12

0.0002***

Absent

13

1

 
  1. FDNs=flat and depressed neoplasias; PNs=protruding neoplasias; CRC=colorectal cancers; NA=not applicable. *P-value calculated by χ2 test; **P-value calculated by Mann–Whitney U-test; ***P-value calculated by Fisher's exact test.
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