Table 3 Toxicity by patient and by cycle (NCI/CTC grade)

From: ‘A phase II study of oral uracil/ftorafur (UFT®) plus leucovorin combined with oxaliplatin (TEGAFOX) as first-line treatment in patients with metastatic colorectal cancer’

 

By patient

By cycle

 

All grades (%)

Grade3–4 (%)

All grades (%)

Grade3–4 (%)

Leucopenia

41

0

21

0

Neutropenia

45

10

23

2

Anaemia

58

6

30

2

Thrombocytopenia

44

14

18

4

Infection

28

10

5

1

Gastrointestinal

    

 Nausea

66

5

33

1

 Vomiting

42

6

25

1

 Diarrhoea

51

11

22

2

 Stomatitis

14

0

6

0

Hand-foot syndrome

3

0

1

0

Sensory neuropathy

89

15

79

3

Asthenia

74

13

33

2

Alopecia

5

0

16

0

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