Table 1 HrHPV type-specific prevalence in adenocarcinoma and its precursors and squamous cell carcinoma vs normal cytology - single infections and single and multiple infections combined

From: Preferential risk of HPV16 for squamous cell carcinoma and of HPV18 for adenocarcinoma of the cervix compared to women with normal cytology in The Netherlands

Type

Normal N =1467

ACIS N =65

AdCx N =70

SCC N =83

Normal vs ACIS

Normal vs AdCx

Normal vs SCC

Multiple a

N (%)

N (%)

N (%)

N (%)

   

 16

440 (30.0)

22 (33.8)

25 (35.7)

58 (69.9)

1.3 (0.7–2.2)

1.3 (0.8–2.2)

7.0 (3.9–12.4)

 18

146 (10.0)

43 (66.2)

40 (57.1)

10 (12.0)

21.8 (11.9–39.8)

15.0 (8.6–26.1)

1.3 (0.6–2.8)

 31

230 (15.7)

3 (4.6)

6 (7.2)

 33

88 (6.0)

3 (3.6)

 35

74 (5.0)

2 (2.4)

 39

70 (4.8)

1 (1.4)

4 (4.8)

1.5 (0.5–4.3)

 45

118 (8.0)

4 (6.2)

8 (11.4)

5 (6.0)

1.6 (0.8–3.5)

 51

98 (6.7)

1 (1.5)

 52

92 (6.3)

1 (1.4)

 56

134 (9.1)

2 (2.4)

 58

93 (6.3)

2 (2.4)

 59

43 (2.9)

 66

100 (6.8)

1 (1.5)

 68

24 (1.6)

Single

N=1221

N=48

N=65

N=74

   

 16

344 (28.2)

14 (29.2)

22 (33.8)

55 (74.3)

1.0 (0.5–1.9)

1.3 (0.7–2.2)

9.2 (4.9–17.3)

 18

108 (8.8)

31 (64.6)

36 (55.4)

8 (10.8)

69.4 (20.8–231.8)

15.8 (8.8–28.4)

1.5 (0.6–3.3)

 31

170 (13.9)

1 (2.1)

3 (4.1)

 33

66 (5.4)

1 (1.4)

 35

48 (3.9)

 39

37 (3.0)

1 (1.5)

1 (1.4)

 45

81 (6.6)

2 (4.2)

6 (9.2)

4 (5.4)

1.5 (0.6–3.2)

 51

60 (4.9)

 52

57 (4.7)

 56

91 (7.5)

 58

60 (4.9)

1 (1.4)

 59

31 (2.5)

 66

59 (4.8)

 68

9 (0.7)

  1. Normal indicates normal cytology; ACIS indicates adenocarcinoma in situ; AdCx indicates adenocarcinoma; SCC indicates squamous cell carcinoma.
  2. Analyses are adjusted for age in 5-year strata.
  3. aMultiple and single infections combined.