Table 1 Analysis of sentinel lymph nodes for the presence of breast cancer metastases by H&E, IHC and RT–PCR

From: Multimarker RT–PCR assay for the detection of minimal residual disease in sentinel lymph nodes of breast cancer patients

   

CK-19

NY-BR-1

MGB-2

 

H&E

IHC

RTPCR

SB

RTPCR

SB a

RTPCR

SB

 1

+

+

a

+

 

+

a

 2

+

+

a

+

 

a

 3

+

+

+

 

++

+++

 4

 

 5

 

 6

+

 

 7

+

+

+

+

+

 

+

+

 8

+

+

+++

+

+++

 

+++

+

 9

 

+

+

10

 

11

 

12

 

13

 

14

 

15

 

+

+

16

 

17

+

 

18

+

 

19

 

20

 

21

++

 

++

++

22

+

+

+

+

+

 

++

+

23

 

24

 

25

 

26

+

+

+++

+

+++

 

+++

+

27

+

+

+++

+

+++

 

+++

+

28

+

+

+

 

++

+

29

 

30

 

  1. aSouthern blot was not performed due to technical reasons.
  2. H&E=haematoxilyn and eosin stain; IHC=immunohistochemistry stain for cytokertain; RT–PCR=reverse transcriptase–polymerase chain reaction; CK-19=cytokeratin-19; MGB-2=mammaglobin-2; SB=southern blot.