Table 1 Demographic and clinical characteristics at baseline (intent-to-treat population, N=173)
Characteristic | Epoetin alfa ( n= 114) | Best standard treatment ( n= 59) |
---|---|---|
Mean age, year (±s.d.) | 59.1 (±10.6) | 60.3 (±11.2) |
Range | 35.0–87.0 | 30.0–79.0 |
Mean Hb level±s.d. (g dl−1) | 10.75±0.94 | 10.66±0.83 |
ECOG performance score (n, %)a | ||
0 | 56 (49.1) | 27 (45.8) |
1 | 47 (41.2) | 29 (49.2) |
2 | 11 (9.6) | 3 (5.1) |
3 | 0 (0.0) | 0 (0.0) |
4 | 0 (0.0) | 0 (0.0) |
Tumour stage, n (%) | ||
I | 12 (10.5) | 10 (16.9) |
II | 13 (11.4) | 3 (5.1) |
III | 58 (50.9) | 32 (54.2) |
IV | 28 (24.6) | 13 (22.0) |
Unknown | 3 (2.6) | 1 (1.7) |
Metastatic disease, n (%) | ||
Unknown | 1 (0.9) | 0 (0.0) |
None | 27 (23.7) | 13 (22.0) |
Abdominal | 66 (57.9) | 32 (54.2) |
Liver | 12 (10.5) | 6 (10.2) |
Lymphatic | 12 (10.5) | 6 (10.2) |
Lung | 7 (6.1) | 5 (8.5) |
Other type | 34 (29.8) | 17 (28.8) |
Previous surgery, n (%) | 94 (82.5) | 49 (83.1) |
Type of chemotherapy, n (%) | ||
Carboplatin | 75 (65.8) | 40 (67.8) |
Carboplatin + paclitaxel | 29 (25.4) | 14 (23.7) |
Cisplatin | 10 (8.8) | 5 (8.5) |