Figure 1
From: Radiosensitivity in breast cancer assessed by the Comet and micronucleus assays
DNA damage assessed by means of the Comet assay in nonirradiated (A) as well as in irradiated (B–D) PBMCs derived from unselected BC patients (circles) and radiation-sensitive (unfilled down triangles) cancer patients compared with the cells from apparently healthy donors (squares). Initial (B), residual (C) DNA damage and the repair half-time constants (D) were assessed in PBMCs after irradiation with 5 Gy in vitro. Filled triangles represent the mean values for the respective group. ‘NS’ indicates that the difference was not highly significant (P>0.05). To facilitate visual comparison, the dashed line is drawn through the mean value of the group of healthy donors. Star and diamond represent the data for patients 016 and 021 who revealed an adverse skin reaction after RT.
